Gregor Townsend has made four changes to the Scotland side that lost so narrowly to New Zealand on Saturday.
The Dark Blues face Australia at BT Murrayfield this weekend after missing out on a historic first win over the All Blacks, where they lost 22-17 in a thrilling encounter.
Ryan Wilson returns to the back row in place of Cornell du Preez after recovering from a shoulder injury, while Sean Maitland is added to the back line after being recently added to the squad.
Grant Gilchrist and Simon Berghan also come into the starting XV, with Ben Toolis and Zander Fagerson dropping to the bench and Lee Jones missing out altogether.
Scotland have enjoyed recent success against the Wallabies and beat them in the summer in Townsend's second match in charge.
The head coach is looking for more of the same.
"Scotland's recent history against Australia has been one of close-fought matches and, after a couple of narrow defeats, we managed to record a win last June out in Sydney," he said.
"Our players have been training hard and will draw on all they've learned in the games against Samoa and New Zealand to rise to the challenge of this final Autumn Test."
He added: "This is the third and final game of our autumn series and the players are looking forward to ending it on a high.
"Last weekend's game was a proper Test match - intense, competitive and full of drama. Unfortunately, we just fell short of our goal, and were disappointed with the loss, but take confidence going into the game against Australia."
— Scottish Rugby (@Scotlandteam) November 22, 2017
Scotland team to play Australia
Forwards: 1 Darryl Marfo (Edinburgh Rugby), 2 Stuart McInally (Edinburgh Rugby), 3 Simon Berghan (Edinburgh Rugby), 4 Grant Gilchrist (Edinburgh Rugby), 5 Jonny Gray (Glasgow Warriors), 6 John Barclay (CAPTAIN, Scarlets), 7 Hamish Watson (Edinburgh Rugby), 8 Ryan Wilson (Glasgow Warriors)
Backs: 9 Ali Price (Glasgow Warriors), 10 Finn Russell (Glasgow Warriors), 11 Sean Maitland (Saracens), 12 Alex Dunbar (Glasgow Warriors), 13 Huw Jones (Glasgow Warriors), 14 Tommy Seymour (Glasgow Warriors), 15 Stuart Hogg (Glasgow Warriors)
Replacements: 16 Fraser Brown (Glasgow Warriors), 17 Jamie Bhatti (Glasgow Warriors), 18 Zander Fagerson (Glasgow Warriors), 19 Ben Toolis (Edinburgh Rugby), 20 Cornell du Preez (Edinburgh Rugby), 21 Henry Pyrgos (Glasgow Warriors), 22 Pete Horne (Glasgow Warriors), 23 Byron McGuigan (Sale Sharks)