Flanker Aaron Wainwright will make his Rugby World Cup debut in Wales' tournament opener against Georgia on Monday.
The 21-year-old features in Wales' starting back-row alongside Justin Tipuric and Josh Navidi, with Ross Moriarty among the replacements.
Skipper Alun Wyn Jones will equal Gethin Jenkins' Wales cap record of 129 appearances when he leads the team out in Toyota City.
Wales head coach Warren Gatland has chosen a starting line-up packed with star names as the Six Nations champions target a flying start.
Jones is joined by fellow British and Irish Lions Test players in Tipuric, full-back Liam Williams, wing George North, centre Jonathan Davies and hooker Ken Owens.
There is also a chance on the bench for fly-half Rhys Patchell, who has recovered from the concussion he suffered during Wales' final World Cup warm-up game against Ireland in Dublin two weeks ago.
Elsewhere, there is a start for Scarlets prop Wyn Jones, and Jake Ball is Alun Wyn Jones' second-row partner with Aaron Shingler providing lock cover among the replacements.
After Georgia, Wales have a six-day turnaround before their Tokyo appointment with Australia that could decide which team wins Pool D.
And Monday's meeting will be Wales' first with Georgia since they posted an unconvincing 13-6 victory over them in Cardiff during the 2017 autumn Tests.
Speaking about Wainwright at a press conference in Toyota, Gatland said: "With Aaron, he is just a player that has continued to improve.
"He's incredibly athletic and an intelligent rugby player. There is only an upward curve for him as a player.
"Since his first cap 12 months or so ago, he's just gone from strength to strength."
Gatland also paid tribute to his skipper Jones as he prepares to equal the Wales cap record. Gatland added: "He has been absolutely outstanding. He has got better with age - he's like a good wine.
"He deserves all the accolades. He's been a great servant to Welsh rugby.
"That recognition hasn't just been in Wales. It's been worldwide.
"It's pleasing to see someone from Wales recognised as one of the best players in his position."
— Welsh Rugby Union (@WelshRugbyUnion) September 21, 2019
Wales team to play Georgia
Forwards: 1 Wyn Jones (Scarlets), 2 Ken Owens (Scarlets), 3 Tomas Francis (Exeter Chiefs), 4 Jake Ball (Scarlets), 5 Alun Wyn Jones (CAPTAIN, Ospreys), 6 Aaron Wainwright (Dragons), 7 Justin Tipuric (Ospreys), 8 Josh Navidi (Cardiff Blues)
Backs: 9 Gareth Davies (Scarlets), 10 Dan Biggar (Northampton Saints), 11 Josh Adams (Cardiff Blues), 12 Hadleigh Parkes (Scarlets), 13 Jonathan Davies (Scarlets), 14 George North (Ospreys), 15 Liam Williams (Saracens)
Replacements: 16 Elliot Dee (Dragons), 17 Nicky Smith (Ospreys), 18 Dillon Lewis (Cardiff Blues), 19 Aaron Shingler (Scarlets), 20 Ross Moriarty (Dragons), 21 Tomos Williams (Cardiff Blues), 22 Rhys Patchell (Scarlets), 23 Leigh Halfpenny (Scarlets)